Geoffrey B Varty: шукати на сайті Z-Library

Рік:

2008

Мова:

english

Файл:

PDF, 189 KB

english, 2008

2-(2-Furanyl)-7-phenyl[1,2,4]triazolo[1,5-c]pyrimidin-5-amine analogs as adenosine A2A antagonists: The successful reduction of hERG activity. Part 2

Julius J. Matasi, John P. Caldwell, Hongtao Zhang, Ahmad Fawzi, Guy A. Higgins, Mary E. Cohen-Williams, Geoffrey B. Varty, Deen B. Tulshian

Журнал:

Julius J. Matasi, John P. Caldwell, Hongtao Zhang, Ahmad Fawzi, Mary E. Cohen-Williams, Geoffrey B. Varty, Deen B. Tulshian

Рік:

2005

Мова:

english

Файл:

PDF, 161 KB

english, 2005

2-(2-Furanyl)-7-phenyl[1,2,4]triazolo[1,5-c]pyrimidin-5-amine analogs: Highly potent, orally active, adenosine A2A antagonists. Part 1

Журнал:

Рік:

2005

Мова:

english

Файл:

PDF, 170 KB

english, 2005

Design, synthesis, and evaluation of fused heterocyclic analogs of SCH 58261 as adenosine A2A receptor antagonists

Unmesh Shah, Claire M. Lankin, Craig D. Boyle, Samuel Chackalamannil, William J. Greenlee, Bernard R. Neustadt, Mary E. Cohen-Williams, Guy A. Higgins, Kwokei Ng, Geoffrey B. Varty, Hongtao Zhang, Jea

Журнал:

Рік:

2008

Мова:

english

Файл:

PDF, 218 KB

english, 2008

Potent and selective adenosine A2A receptor antagonists: 1,2,4-Triazolo[1,5-c]pyrimidines

Bernard R. Neustadt, Hong Liu, Jinsong Hao, William J. Greenlee, Andrew W. Stamford, Carolyn Foster, Leyla Arik, Jean Lachowicz, Hongtao Zhang, Rosalia Bertorelli, Silva Fredduzzi, Geoffrey Varty, Mar

Журнал:

Рік:

2009

Мова:

english

Файл:

PDF, 199 KB

english, 2009

Identification of 3-substituted N-benzhydryl-nortropane analogs as nociceptin receptor ligands for the management of cough and anxiety

Shu-Wei Yang, Ginny Ho, Deen Tulshian, William J. Greenlee, Zheng Tan, Hongtao Zhang, April Smith-Torhan, Ahmad Fawzi, John Anthes, Sherry Lu, Geoffrey Varty, Xiomara Fernandez, Robbie L. McLeod, John

Журнал:

Рік:

2009

Мова:

english

Файл:

PDF, 897 KB

english, 2009

Tetrahydroquinoline sulfonamides as vasopressin 1b receptor anatgonists

Jack D. Scott, Michael W. Miller, Sarah W. Li, Sue-Ing Lin, Henry A. Vaccaro, Liwu Hong, Deborra E. Mullins, Mario Guzzi, Jay Weinstein, Robert A. Hodgson, Geoffrey B. Varty, Andrew W. Stamford, Tin-Y

Журнал:

Рік:

2009

Мова:

english

Файл:

PDF, 1.01 MB

english, 2009

Discovery of a series of potent, orally active α,α-disubstituted piperidine NK1 antagonists

Dong Xiao, Cheng Wang, Anandan Palani, Hon-Chung Tsui, Gregory Reichard, Sunil Paliwal, Neng-Yang Shih, Robert Aslanian, Ruth Duffy, Jean Lachowicz, Geoffrey Varty, Cynthia Morgan, Fei Liu, Amin Nomei

Журнал:

Geoffrey B. Varty, Robert A. Hodgson, Annamarie J. Pond, Michael E. Grzelak, Eric M. Parker, John C. Hunter

Рік:

2010

Мова:

english

Файл:

PDF, 1.31 MB

english, 2010

The antinociceptive and anxiolytic-like effects of the metabotropic glutamate receptor 5 (mGluR5) antagonists, MPEP and MTEP, and the mGluR1 antagonist, LY456236, in rodents: a comparison of efficacy and side-effect profiles

Geoffrey B. Varty, Mariagrazia Grilli, Angelo Forlani, Silva Fredduzzi, Michael E. Grzelak, Donald H. Guthrie, Robert A. Hodgson, Sherry X. Lu, Elisa Nicolussi, Annamarie J. Pond, Eric M. Parker, John

Журнал:

Psychopharmacology

Рік:

2005

Мова:

english

Файл:

PDF, 186 KB

english, 2005

The effects of adenosine A2Areceptor antagonists on haloperidol-induced movement disorders in primates

Журнал:

Psychopharmacology

Рік:

2008

Мова:

english

Файл:

PDF, 206 KB

english, 2008

Procognitive and antipsychotic efficacy of glycine transport 1 inhibitors (GlyT1) in acute and neurodevelopmental models of schizophrenia: latent inhibition studies in the rat

Mark D. Black, Geoffrey B. Varty, Michal Arad, Segev Barak, Amaya De Levie, Denis Boulay, Philippe Pichat, Guy Griebel, Ina Weiner

Журнал:

Psychopharmacology

Рік:

2009

Мова:

english

Файл:

PDF, 255 KB

english, 2009

Cyclobutane derivatives as potent NK1 selective antagonists

Michelle Laci Wrobleski, Gregory A. Reichard, Sunil Paliwal, Sapna Shah, Hon-Chung Tsui, Ruth A. Duffy, Jean E. Lachowicz, Cynthia A. Morgan, Geoffrey B. Varty, Neng-Yang Shih

Журнал:

Timothy J. Kowalski, Constance Farley, Mary E. Cohen-Williams, Geoffrey Varty, Brian D. Spar

Рік:

2006

Мова:

english

Файл:

PDF, 134 KB

english, 2006

Increased auditory startle response and reduced prepulse inhibition of startle in transgenic mice expressing a double mutant form of amyloid precursor protein

Martha F McCool, Geoffrey B Varty, Robert A Del Vecchio, Tatiana M Kazdoba, Eric M Parker, John C Hunter, Lynn A Hyde

Журнал:

Brain Research

Рік:

2003

Мова:

english

Файл:

PDF, 597 KB

english, 2003

Melanin-concentrating hormone-1 receptor antagonism decreases feeding by reducing meal size

Журнал:

Рік:

2004

Мова:

english

Файл:

PDF, 159 KB

english, 2004

Pharmacological profile of the NOP agonist and cough suppressing agent SCH 486757 (8-[Bis(2-Chlorophenyl)Methyl]-3-(2-Pyrimidinyl)-8-Azabicyclo[3.2.1]Octan-3-Ol) in preclinical models

Robbie L. McLeod, Deen B. Tulshian, Donald C. Bolser, Geoffrey B. Varty, Marco Baptista, Xiomara Fernandez, Leonard E. Parra, Jennifer C. Zimmer, Christine H. Erickson, Ginny D. Ho, Yanlin Jia, Fay W.

Журнал:

Robert A. Hodgson, Donald H. Guthrie, Geoffrey B. Varty

Рік:

2010

Мова:

english

Файл:

PDF, 942 KB

english, 2010

Duration of ultrasonic vocalizations in the isolated rat pup as a behavioral measure: Sensitivity to anxiolytic and antidepressant drugs

Журнал:

Рік:

2008

Мова:

english

Файл:

PDF, 448 KB

english, 2008

The neurokinin NK2 antagonist, saredutant, ameliorates stress-induced conditions without impairing cognition

Nancy Rogacki, Matilde Lopez-Grancha, Vanessa Naimoli, Lisa Potestio, Rachel J. Stevens, Philippe Pichat, Olivier E. Bergis, Caroline Cohen, Geoffrey B. Varty, Guy Griebel

Журнал:

Robert A. Hodgson, Lynn A. Hyde, Donald H. Guthrie, Mary E. Cohen-Williams, Prescott T. Leach, Tatiana M. Kazdoba, Carina J. Bleickardt, Sherry X. Lu, Eric M. Parker, Geoffrey B. Varty

Рік:

2011

Мова:

english

Файл:

PDF, 518 KB

english, 2011

Characterization of the selective mGluR1 antagonist, JNJ16259685, in rodent models of movement and coordination

Журнал:

Рік:

2011

Мова:

english

Файл:

PDF, 698 KB

english, 2011

Rolapitant (SCH 619734): A potent, selective and orally active neurokinin NK1 receptor antagonist with centrally-mediated antiemetic effects in ferrets

Ruth A. Duffy, Cynthia Morgan, Robert Naylor, Guy A. Higgins, Geoffrey B. Varty, Jean E. Lachowicz, Eric M. Parker

Журнал:

Рік:

2012

Мова:

english

Файл:

PDF, 569 KB

english, 2012

SAR110894, a potent histamine H3-receptor antagonist, displays procognitive effects in rodents

Guy Griebel, Philippe Pichat, Marie-Pierre Pruniaux, Sandra Beeské, Mati Lopez-Grancha, Elisabeth Genet, Jean-Paul Terranova, Antonio Castro, Juan Antonio Sánchez, Mark Black, Geoffrey B. Varty, Ina W

Журнал:

Geoffrey B Varty, Charles A Marsden, Guy A Higgins

Рік:

2012

Мова:

english

Файл:

PDF, 968 KB

english, 2012

Reduced synaptophysin immunoreactivity in the dentate gyrus of prepulse inhibition-impaired isolation-reared rats

Журнал:

Brain Research

Рік:

1999

Мова:

english

Файл:

PDF, 576 KB

english, 1999

Comparison of apomorphine, amphetamine and dizocilpine disruptions of prepulse inhibition in inbred and outbred mice strains

Geoffrey B Varty, Nafesa Walters, Mary Cohen-Williams, Galen J Carey

Журнал:

Colin N Haile, Galen Carey, Geoffrey B Varty, Vicki L Coffin

Рік:

2001

Мова:

english

Файл:

PDF, 289 KB

english, 2001

The dopamine D1 receptor agonist SKF-82958 serves as a discriminative stimulus in the rat

Журнал:

Рік:

2000

Мова:

english

Файл:

PDF, 154 KB

english, 2000

The Gerbil Elevated Plus-maze II: Anxiolytic-like Effects of Selective Neurokinin NK1 Receptor Antagonists

Geoffrey B Varty, Mary E Cohen-Williams, Cynthia A Morgan, Ursula Pylak, Ruth A Duffy, Jean E Lachowicz, Galen J Carey, Vicki L Coffin

Журнал:

Geoffrey B Varty, Cynthia A Morgan, Mary E Cohen-Williams, Vicki L Coffin, Galen J Carey

Рік:

2002

Мова:

english

Файл:

PDF, 523 KB

english, 2002

The Gerbil Elevated Plus-Maze I: Behavioral Characterization and Pharmacological Validation

Журнал:

Рік:

2002

Мова:

english

Файл:

PDF, 1.13 MB

english, 2002

Discrepant Findings of Clozapine Effects on Prepulse Inhibition of Startle: Is It the Route or the Rat?

Neal R. Swerdlow, M.D., Ph.D, Geoffrey B. Varty, Ph.D, Mark A. Geyer, Ph.D

Журнал:

Geoffrey B Varty, Vaishali P Bakshi, Mark A Geyer

Рік:

1998

Мова:

english

Файл:

PDF, 192 KB

english, 1998

M100907, a Serotonin 5-HT2A Receptor Antagonist and Putative Antipsychotic, Blocks Dizocilpine-Induced Prepulse Inhibition Deficits in Sprague–Dawley and Wistar Rats

Журнал:

Mark A Geyer, Kirsten Krebs-Thomson, Geoffrey B Varty

Рік:

1999

Мова:

english

Файл:

PDF, 357 KB

english, 1999

The Effects of M100907 in Pharmacological and Developmental Animal Models of Prepulse Inhibition Deficits in Schizophrenia

Журнал:

Geoffrey B. Varty, Guy A. Higgins

Рік:

1999

Мова:

english

Файл:

PDF, 166 KB

english, 1999

Reversal of a dizocilpine-induced disruption of prepulse inhibition of an acoustic startle response by the 5-HT2 receptor antagonist ketanserin

Журнал:

Geoffrey B. Varty, Susan B. Powell, Virginia Lehmann-Masten, Mahalah R. Buell, Mark A. Geyer

Рік:

1995

Мова:

english

Файл:

PDF, 481 KB

english, 1995

Isolation rearing of mice induces deficits in prepulse inhibition of the startle response

Журнал:

Behavioural Brain Research

Рік:

2006

Мова:

english

Файл:

PDF, 250 KB

english, 2006

The effect of caffeine to increase reaction time in the rat during a test of attention is mediated through antagonism of adenosine A2A receptors

Guy A. Higgins, Michael E. Grzelak, Annamarie J. Pond, Mary E. Cohen-Williams, Robert A. Hodgson, Geoffrey B. Varty

Журнал:

Behavioural Brain Research

Рік:

2007

Мова:

english

Файл:

PDF, 903 KB

english, 2007

The genetic liability to stress and postweaning isolation have a competitive influence on behavioral organization in rats

Martin P. Paulus, Geoffrey B. Varty, Mark A. Geyer

Журнал:

Physiology & Behavior

Рік:

2000

Мова:

english

Файл:

PDF, 146 KB

english, 2000

Is there a critical developmental `window' for isolation rearing-induced changes in prepulse inhibition of the acoustic startle response?

Geoffrey B Varty, David L Braff, Mark A Geyer

Журнал:

Behavioural Brain Research

Рік:

1999

Мова:

english

Файл:

PDF, 198 KB

english, 1999

Preladenant, a selective A2A receptor antagonist, is active in primate models of movement disorders

Robert A. Hodgson, Paul J. Bedard, Geoffrey B. Varty, Tatiana M. Kazdoba, Therese Di Paolo, Michael E. Grzelak, Annamarie J. Pond, Abdallah HadjTahar, Nancy Belanger, Laurent Gregoire, Aurelie Dare, B

Журнал:

Experimental Neurology

Рік:

2010

Мова:

english

Файл:

PDF, 484 KB

english, 2010

Environmental enrichment and isolation rearing in the rat: effects on locomotor behavior and startle response plasticity

Geoffrey B Varty, Martin P Paulus, David L Braff, Mark A Geyer

Журнал:

Biological Psychiatry

Рік:

2000

Мова:

english

Файл:

PDF, 274 KB

english, 2000

Investigations into the nature of a 7-OH-DPAT discriminative cue: Comparison with d-amphetamine

Geoffrey B Varty, Guy A Higgins

Журнал:

Journal of Medicinal Chemistry

Рік:

1997

Мова:

english

Файл:

PDF, 167 KB

english, 1997

Piperazine-Based CCR5 Antagonists as HIV-1 Inhibitors. IV. Discovery of 1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]- 4-[4-{2-methoxy-1( R )-4-(trifluoromethyl)phenyl}ethyl-3( S )-methyl-1-piperazinyl]- 4-methylpiperidine (Sch-417690/Sch-D), a Potent, Highly Selective, and Orally Bioavailable CCR5 Antagonist

Tagat, Jayaram R., McCombie, Stuart W., Nazareno, Dennis, Labroli, Marc A., Xiao, Yushi, Steensma, Ruo W., Strizki, Julie M., Baroudy, Bahige M., Cox, Kathleen, Lachowicz, Jean, Varty, Geoffrey, Watki

Журнал:

Рік:

2004

Мова:

english

Файл:

PDF, 78 KB

english, 2004

Characterization of a novel vasopressin V1b receptor antagonist, V1B-30N, in animal models of anxiety-like and depression-like behavior

Hodgson, Robert A., Mullins, Deborra, Lu, Sherry X., Guzzi, Mario, Zhang, Xiaoping, Bleickardt, Carina J., Scott, Jack D., Miller, Michael W., Stamford, Andrew W., Parker, Eric M., Varty, Geoffrey B.

Журнал: